CAS：124-68-5|The application of AMP in the treatment of eye diseases

2-Amino-2-methyl-1-propanol (AMP, CAS 124-68-5) is an organic compound with the molecular formula C6H15NO5S and a molecular weight of 89.14. AMP can be used as a vulcanization accelerator, acidic gas absorber, and additive for coatings, with pigment dispersion, pH adjustment, and rust prevention effects. In addition, AMP can also be used in ophthalmic compositions to treat diseases such as dry eye disease. CN107072942A patent has developed a ophthalmic composition. This week, the editor of YACOO will briefly introduce the composition of the ophthalmic composition.
The ophthalmic composition comprises polyquaternary ammonium salt compounds, anionic polymers, effective amounts of organic acids, organic acid salts, or mixtures thereof.
Polyquaternary ammonium salt compound is selected as polyquaternary ammonium salt 42;
Anionic polymers are selected from hyaluronic acid, gelled adhesive, alkyl vinyl ether/maleic anhydride copolymers, and their mixtures;
Organic acids include but are not limited to carboxylic acids, dicarboxylic acids, tricarboxylic acids, their salts, and their mixtures;
The composition of the present invention may also optionally include one or more other excipients or active ingredients. Excipients can be relaxants, stretching agents, preservatives, chelating agents, buffering agents, and surfactants.
The buffer can be phosphate, borate, acetate, amino alcohol (2-amino-2-methyl-1-propanol), etc.
The ophthalmic composition comprises a combination of polyquaternary ammonium salt compounds, anionic polymers, and an effective amount of organic acids, which inhibits the precipitation and complexation of polyquaternary ammonium salt compounds and anionic polymers.

Reference
CN107072942A Ophthalmic composition.