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2 US doctors infected Ebola virus received experimental drug treatment
2014-08-05
来源：转载自第三方
According to the US Cable News Network reported that two medical staff infected Ebola virus in Liberia returned to the United States and have been injected with a experimental drug "ZMapp" developed by a San Diego biopharmaceutical company, the physical condition improved significantly.
According to the latest data released by the World Health Organization on Monday, the number of people currently killed in Guinea, Sierra Leone, Liberia and Nigeria due to infection with Ebola virus has reached 887.
Because of the current lack of effective treatment, and no vaccine can prevent Ebola, the experimental drug caused a lot of questions. According to reports, the drug was developed by a biotechnology company called "Mapp Biopharmaceutical Inc." in San Diego, USA, which was founded in 2003 with only nine employees. According to the company website, the company is committed to the prevention and treatment of infectious diseases to develop new drugs, concerned about the demand of global health and biochemical defense did not meet the.
The company has worked with the National Institutes of National Health and the National Defense Threat Reduction Agency, which is responsible for weapons of mass destruction, for several years to develop drugs for the treatment of Ebola virus.
However, the drugs used for the treatment have not been tested at present. It was reported that after two US medical volunteers agreed, they were injected with the drug, and they understood that the drug had not been tested. This is in line with the US Food and Drug Administration "compassionate use" requirement.
It is unclear whether the drug is ultimately effective. The condition of the two American patients needs to be further observed to see how the drug works with its immune system. It is unclear whether the drug can be applied to other patients. According to a spokesman from the World Health Organization, doctors can not use untested drugs in the outbreak of the disease. And now the company has no extra drugs to other patients.
Other agencies in the United States are also actively developing related drugs. According to reports, the US National Institutes of Health in March this year received a funding of five-year 28 million US dollars, and work with other 15 institutions to study against the Ebola virus. It has been shown that different antibiotics have a potential therapeutic effect after mixing, but the researchers are still trying which combination is most effective and how they work.
A company in Vancouver and the US Department of Defense signed a $140 million contract to develop drugs for the treatment of Ebola virus, in January they has begun the first phase of the drug test, but the US Food and Drug Administration has recently stopped the drug experiment.
It is reported that at least one kind of Ebola vaccine has been used in healthy volunteers who carry out human trials. Last week, the National Institutes of Health announced that it would start another safety trial in September.
TAG: Chemical Reagents, Biomedicine
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