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New studies: Factors that may increase the risk of type II diabetes
2017-02-08
来源：亚科官网
7 February 2017
Diabetes is a chronic disease, when the pancreas can not produce enough insulin or when the body can not effectively use the insulin, there will be diabetes, leading to elevated blood glucose levels. Type II diabetes is due to the human body can not effectively use of insulin. In the world, the vast majority of patients are with type II diabetes. WHO calls for action to reduce exposure to risk factors for type II diabetes to reduce the risk of disease. In addition to overweight and physical inactivity, what other factors that increase the risk of type II diabetes? This article will introduce several new studies, scientists have proposed several factors that may increase the risk of type II diabetes.
In March last year, researchers at the University of Campinas in Sao Paulo found that adipose tissue accumulation and insulin sensitivity are more likely in adolescents with nocturnal sleep less than eight hours, and these can lead to type II diabetes. The researchers analyzed data on 615 adolescents (aged 10~19 years) between 2011 and 2014. Eighty-one participants also received a 2-hour insulin sensitivity test. Compared with participants who had more sleep, 257 participants who had less than 8 hours of sleep per night were older, heavier and taller, and had greater waist and neck circumference. Participants with less sleep had lower insulin sensitivity than those had more sleep. Several adult studies have shown that sleep deprivation is associated with an increased risk of cardiovascular disease, including obesity and an increased incidence of diabetes.
Subsequently, the American Endocrine Society annual meeting published a study. Hypothyroidism is related with the increased risk of type II diabetes. The study included 8,452 residents of Rotterdam (aged≥45 years) and they did not have diabetes. During an average of 7.9 years of follow-up, 1,100 participants progressed to pre-diabetes and 798 with type II diabetes. After adjusting for confounding factors such as gender, age, smoking, and fasting glucose, the risk of type II diabetes for participants in the highest TSH group is 1.13 times compared with the lowest group.
Researchers from institutions of Carolyn College in Sweden have shown that the risk of type II diabetes increases by 70% if a daily intake of one pack or more of snuff (snuff is a smokeless tobacco product made from fermented tobacco powder and nasally ingested). The researchers analyzed data from 54,500 men during the period 1990~2013, 2,441 individuals diagnosed with type II diabetes during the study period and 40% increased risk of type II diabetes in individuals with low levels of snuff intake. Perhaps the explanation for this possibility is the effect of nicotine, which can impair the body's insulin sensitivity and increase the risk of type II diabetes. Similarly, smoking may also increase the risk of type II diabetes.
In addition, studies have shown that excessive intake of sugary beverages, unreasonable breakfast, and congenital heart disease, etc. will also increase the risk of type II diabetes. Diabetes is incurable, and only can be regulated by drugs. In terms of therapies, metformin is still the best type II diabetes drug, based on ACP's latest guidelines. It can be used alone or in combination with other drugs to lower blood sugar levels, including sulfonylureas, thiazolidinediones, SGLT-2 inhibitors or DPP-4 inhibitors.
To improve the living quality of people with diabetes, drug therapy is very important, but to beat diabetes, preventive measures are the most important: maintaining a healthy lifestyle, reasonable diet, increasing exercise to improve endocrine system function, increasing the body's disease resistance ability to inhibit obesity, promoting oxidative transport of glucose, and maintaining a happy mood. Reduce the risk of exposure to the disease in order to effectively reduce the possibility.
Edited by the Editorial Office of Suzhou Yacoo Science Co., Ltd.
