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利塞膦酸盐（105462-24-6）抗男性骨质疏松性骨折的效应
2014-08-27
来源：亚科官网
亚科化学试剂带领大家探讨下利塞膦酸盐（105462-24-6）抗男性骨质疏松性骨折的效应：
方法 通过Medline数据库、EMBASE数据库、Cochrane图书馆和中国生物医学文献数据库检索1980-01至2006-12有关利塞膦酸盐与安慰剂治疗男性骨质疏松患者的随机对照试验.随访大于12个月,提供骨折发生率的文献纳入研究.分析入选文献的方法学质量,提取资料,用RevMan 4.2软件进行荟萃分析.结果 3篇文献符合纳入标准,包括780例男性骨质疏松患者.荟萃分析结果显示利塞膦酸盐可降低69%的椎体骨折风险(RR=0.31,95% CI:0.16,0.60)和58%的非椎体骨折风险(RR=0.42,95% CI:0.23,0.78).结论 利塞膦酸盐对男性骨质疏松症患者可提供良好的抗骨折效应.
参考文献(25条)
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